Ecotoxicology & Environmental Risk Assessment Services
Understanding and mitigating the environmental impact of chemicals is critical for regulatory compliance under REACH, the Biocidal Products Regulation (BPR), the Plant Protection Products Regulation (PPP), and for human (HMP) and veterinary (VMP) medicinal products. At Blue Frog Scientific, we provide specialist ecotoxicology and environmental risk assessment services, ensuring that your substances and products meet EU and UK regulatory requirements while supporting sustainable environmental practices.
Our team of ecotoxicologists and environmental risk assessors combines scientific expertise with regulatory insight, delivering high-quality studies, strategic risk assessments, and regulatory guidance tailored to your industry sector.
Regulatory Ecotoxicology and Compliance Strategy
Our regulatory ecotoxicology services provide clients with the necessary expertise, guidance, and assurance that their environmental assessment strategies for chemicals, biocides, plant protection products, and pharmaceuticals are comprehensive and compliance with the necessary legislative information requirements.
Our services include:
- Regulatory Strategy Development – Providing expert guidance on efficient and effective compliance with environmental requirements under REACH, BPR, PPP, and HMP/VMP reulgations
- Literature Search & Systematic Review – Conducting scientific literature evaluations to support information requirements and weight-of-evidence approaches
- Data Gap Analysis & Integrated Testing Strategies – Identifying missing data and designing cost-effective, scientifically robust testing plans that align with regulatory expectations
- Dossier Compilation & Submission – Preparing scientifically robust environmental dossier sections for REACH, biocides, and plant protection products
- Regulatory Advocacy & Stakeholder Engagement – Representing clients in substance evaluations, regulatory reviews, and compliance checks to ensure proportional and science-driven decision-making
- Endocrine Disruption Strategy - Depending on which sector of the chemical industry you are addressing, the regulatory profile of your chemical, and it’s intrinsic properties, we can develop an appropriate strategy for complying with assessment of environmental endocrine disruption
Specialist Ecotoxicology & Technical Services
Our specialist ecotoxicology services blend environmental assessment of compounds with strict regulatory information requirements, to ensure relevance and reliability of ecotoxicological data for your submission. Correct interpretation and application of these data in hazard and risk assessment are also integral to our service offering.
Our Environmental Safety Team provides full study design, placement, and independent monitoring services, ensuring high-quality, compliant toxicological data.
We cover all relevant toxicological areas, including:
- Avian Toxicology:
- Acute & Chronic Toxicity Studies – Conducting dietary and oral toxicity tests to determine the impact of chemicals on bird populations
- Aquatic Toxicology:
- Invertebrates – Conducting acute and chronic toxicity tests on species such as Daphnia to assess effects on aquatic ecosystem health
- Vertebrates – Evaluating short-term and long-term toxicity in fish, including developmental and reproductive effects
- Aquatic Plants – Assessing phytotoxic effects of chemicals on aquatic plant species using growth inhibition studies
- Terrestrial Toxicology:
- Pollinators – Performing acute, chronic, and larval toxicity assessments to evaluate the impact of agrochemicals on bees and pollinator health
- Non-Target Arthropods (NTAs) – Conducting field and semi-field studies to assess effects on beneficial insect populations
- Environmental Endocrine Disruption:
- Tiered Testing & Weight-of-Evidence Approaches – Evaluating endocrine activity, adverse effects, and mode of action (MOA) of substances in environmental species
- Specialist Studies – Including the Extended One Generation Reproduction Test (e.g. MEOGRT) to assess endocrine disruption in aquatic organisms
Environmental Risk Assessment (ERA)
We provide comprehensive environmental risk assessments (ERA) for chemicals, biocides, and plant protection products, covering:
- Hazard Assessment – Evaluating intrinsic hazardous properties of a substance, including toxicity to aquatic and terrestrial organisms, bioaccumulation, mobility, and persistence in the environment (PBT/PMT)
- Exposure Assessment – Estimating environmental concentrations (PECs) using industry specific modelling tools and measured data, covering surface water, sediment, soil, and air
- Risk Characterisation – Comparing predicted environmental concentrations (PECs) to predicted no-effect concentrations (PNECs), or utilising toxicity:exposure ratios to determine acceptability of risk compared to regulatory benchmarks
- Risk Mitigation Strategies – Developing risk management measures, including use restrictions, formulation adjustments, application rate modifications, and environmental monitoring programs to minimise ecological impact
- Safety Reporting - Compilation of relevant environmental risk assessment reports (e.g. CSR, DAR, dRR) in support of chemical, biocide, plant protection product, and pharmaceutical submissions
Our risk assessments align with ECHA, EFSA, HSE, EMA, MHRA, and VMD methodologies, ensuring compliance with current regulatory expectations while balancing scientific robustness and practicality.
At Blue Frog Scientific, we provide scientifically robust, regulatory compliant environmental risk assessments to support chemical, biocide, plant protection product, and pharmaceutical registrations. Our highly qualified team, with backgrounds in regulatory agencies, industry, and research, ensures that your environmental dossiers and risk assessments meet the highest regulatory standards.
